EDT - Home

Revealing the invisible Can you imagine seeing molecules in solution?

Imagine easily seeing molecules in your sample solution during daily work. Like never before, EDT visualizes molecules in solution based on electron density maps.

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Free from anchoring Is special sample preparation needed for analysis?

Established structural methods require the generation of specialized samples for structural analysis in addition to your research. With EDT, you can observe the molecules in your sample solution without further preparation. EDT requires no anchoring processes, such as crystallization or freezing, and also requires no labeling.

Learn about EDT

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What is EDT?

The technology visualizes the shape and clarifies the dynamic characteristics of molecules in solution, including antibodies, protein complexes, and virus particles. EDT utilizes the interactions between the electron density distribution of molecules and X-rays, unveiling unseen properties of your molecule by observing both their shape and behavior.

Turning the impossible into reality

Did you know…

Established structural methods require the generation of samples for structural analysis in addition to your research. This requires designing specific molecules followed by sample expression and preparation using specialized skills. To make this possible, experts in structural analysis are needed. EDT enables all researchers to utilize 3D information of the molecule in their sample; thus, it is ideal for gaining insights into novel molecules in your daily work, allowing you to visualize their shape and behavior.

Turnkey for everyone

No specialized skills are required to observe molecules using EDT. Simply place the solution sample in the instrument and start the run.

Solutions available for you

Whether you're in academia or industry, we can provide the instrument for your institution or project-based contract services. Our solutions provide complementary workflows based on 3D information in modality design, development and quality assurance.

Demo the future today

A brand-new demo lab is opening very soon in Cambridge, Massachusetts. You can now request a demonstration of the EDT capability with your actual samples in Japan or the United States.

The process How to get started

Contact us to discuss your specific molecular research needs and challenge EDT with your samples. Once you've reviewed the results, you can decide whether to continue with our contract services or invest in the EDT system.

Your turn Get a demo

Utilize our cutting-edge lab at SmartLabs in Cambridge, Massachusetts, to observe your molecules without the need to invest in equipment. We also offer demonstrations in Japan. Review the results for yourself and decide on the best path forward.

Request a Demo

Observe Your Molecules On-demand

No more guesswork

Visualize molecules in solution with the EDT (Electron Density Topography) method, eliminating guesswork in daily study for modality design and characterization in drug development.

The industry challenge